Biomimetic filler that restores the skin's lipid structure
Reduces water loss and improves skin elasticity
7 days long-lasting effect
This effect of Bicosome® FS is visualized in cryo-SEM studies on skin teated with Bicosome® FS. The smart disc bilayer structures are visible while being anchored in the inter-cellular spaces of the Stratum Corneum.
Bicosome® FS improves barrier function and biomechanical properties of skin during use. However, due to the intrinsic repair of of the skin's lipid structure it also has an ongoing and prolonged effect that continues for at least 7 days after application has stopped.
In-vivo clinical studies on 20 volunteers show that barrier function, as measured by water loss, is improved by 25% 7 days after finishing a 7-day application regimen compared to non-treated skin. Skin elasticity and firmness also continue to improve as well.
Bicosome® FS also helps repair damages to the skin barrier after it has been disrupted by chemical aggression (e.g. as exposure to salicylic acid, sodium lauryl sulphate, etc.).
In the same clinical study on 20 volunteers skin was exposued for 2 hours to sodium lauryl sulphate after which a 7-day application regimen was started with Bicosome® FS (1 daily application). barrier function, as measured by water loss, is restored much quicker due to Bicosome® FS (4 versus 7 days) and Firmness and elasticity are fully restored after 2 daily applications.
Application, benefits, and claims
Bicosome® FS can be used in a variety of products:
Skin care, sun care, lip care:
• Intrinsic repair of lipid structures and the Stratum Corneum
• Mimicking basal epidermal layer's activity in lipid replenishment
• Repairs damage caused by aggressive chemicals
• Quicker recovery of barrier and biochemical properties
• Long-lasting effect, even after application has stopped
Liquid water-based Bicosome® FS:
Lyophilized Bicosome® FS:
Dos and Don’ts:
Bicowhite® is globally compliant (including China) for use as cosmetic ingredient
Bicosome® FS : Aqua, Lecithin, Hydrogenated Phosphatidylcholine, Lysolecithin, Sodium Benzoate, Citric Acid, Potassium Sorbate, Phytic Acid, Tocopherol (mixed), Beta-Sitosterol, Squalane
Bicosome® FS - Lyophilized: Lecithin, Hydrogenated Phosphatidylcholine, Lysolecithin, Sodium Benzoate, Citric Acid, Potassium Sorbate, Phytic Acid, Tocopherol (mixed), Beta-Sitosterol, Squalane, Aqua
The Bicosome® products are developed and manufactured by Bicosome company (www.bicosome.com). Ultra is the supplier of the Bicosome® products in parts of the US and Canada.
Bicosome® FS is a 99% natural ingredient based on the Bicosome® skin delivery platform. The Bicosome® platform is focused around lipid bilayer structures that are called smart discs. The smart discs in Bicosome® FS are designed to penetrate into the intermediate layers of the Stratum Corneum.
Once these intermediate layers are reached, the lipid structures of the smart discs replenish, rebuild and reinforce the skin's natural lipid matrix. In this way Bicosome® FS performs a similar role and mimics the biological activity of basal epidermal layers that replenish lipids via lamelar bodies.
SAXS (Small Angle X-ray Scattering) of native and Bicosome® FS treated skin samples show a higher degree of organization of lipid structures which relates to a stronger barrier function. This is indicated in the SAXS spectrum by the increase in number and sharpening of peaks after Bicosome® FS treatment.